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We may fondly imagine that we are impartial seekers after truth, but with a few exceptions, to which I know that I do not belong, we are influenced, and sometimes strongly, by our personal bias; and we give our best thoughts to those ideas which we have to defend.

Nevertheless, we should of course all do our best to avoid controversy, in the sense that we should take every possible care to verify our facts and substantiate our conclusions before we publish our results.

August Krogh
August Krogh (1874-1949) Danish zoophysiologist, academic
“The Progress of Physiology,” Speech, International Congress of Physiological Sciences, Harvard University (1929-08-19)
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Reprinted in Science (1929-08-30). Quoted in Bodil Schmidt-Nielsen, August and Marie Krogh: Lives in Science, ch. 9 (1995).
 
Added on 13-Jun-23 | Last updated 13-Jun-23
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Progress in science is often built on wrong theories that are later corrected. It is better to be wrong than to be vague.

Freeman Dyson
Freeman Dyson (1923-2020) English-American theoretical physicist, mathematician, futurist
The Scientist as Rebel, Part 3, ch. 19 “The World on a String” (2006)
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Originally published in New York Review of Books (2003-11-06).
 
Added on 3-Apr-23 | Last updated 3-Apr-23
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Science is in far greater danger from the absence of challenge than from the coming of any number of even absurd challenges.

Isaac Asimov (1920-1992) Russian-American author, polymath, biochemist
“The Role of the Heretic,” Foreword to Donald W. Goldsmith (ed.), Scientists Confront Velikovsky (1977)
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Added on 3-Nov-21 | Last updated 3-Nov-21
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A fact is a simple statement that everyone believes. It is innocent, unless found guilty. A hypothesis is a novel suggestion that no one wants to believe. It is guilty, until found effective.

Edward Teller (1908-2003) Hungarian-American theoretical physicist
Conversations on the Dark Secrets of Physics, ch. 5 (1991) [with Wendy Teller, Wilson Talley]
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Added on 2-Mar-21 | Last updated 2-Mar-21
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Details that could throw doubt on your interpretation must be given, if you know them. You must do the best you can — if you know anything at all wrong, or possibly wrong — to explain it. If you make a theory, for example, and advertise it, or put it out, then you must also put down all the facts that disagree with it, as well as those that agree with it. There is also a more subtle problem. When you have put a lot of ideas together to make an elaborate theory, you want to make sure, when explaining what it fits, that those things it fits are not just the things that gave you the idea for the theory; but that the finished theory makes something else come out right, in addition. In summary, the idea is to try to give all of the information to help others to judge the value of your contribution; not just the information that leads to judgment in one particular direction or another.

Richard Feynman (1918-1988) American physicist
“Cargo Cult Science,” commencement address, California Institute of Technology (1974)
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Added on 22-Jan-20 | Last updated 22-Jan-20
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Don’t you believe in flying saucers, they ask me? Don’t you believe in telepathy? — in ancient astronauts? — in the Bermuda triangle? — in life after death?

No, I reply. No, no, no, no, and again no.

One person recently, goaded into desperation by the litany of unrelieved negation, burst out “Don’t you believe in anything?”

“Yes”, I said. “I believe in evidence. I believe in observation, measurement, and reasoning, confirmed by independent observers. I’ll believe anything, no matter how wild and ridiculous, if there is evidence for it. The wilder and more ridiculous something is, however, the firmer and more solid the evidence will have to be.”

Isaac Asimov (1920-1992) Russian-American author, polymath, biochemist
The Roving Mind (1983)
 
Added on 2-Aug-16 | Last updated 2-Aug-16
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Science, my lad, has been built upon many errors; but they are errors which it was good to fall into, for they led to the truth.

[La science, mon garçon, est faite d’erreurs, mais d’erreurs qu’il est bon de commettre, car elles mènent peu à peu à la vérité.]

Verne - science and error - wist_info quote

Jules Verne (1828-1905) French novelist, poet, playwright
Journey to the Center of the Earth, ch. 31 (1864) [tr. Malleson (1877)]
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Alt. trans.: "Science, my lad, is made up of mistakes, but they are mistakes which it is useful to make, because they lead little by little to the truth."
 
Added on 4-Mar-16 | Last updated 10-Mar-16
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Indeed, proof that a given condition always precedes or accompanies a phenomenon does not warrant concluding with certainty that a given condition is the immediate cause of that phenomenon. It must still be established that when this condition is removed, the phenomenon will no longer appear.

Claude Bernard (1813-1878) French physiologist, scientist
An Introduction to the Study of Experimental Medicine [Introduction à l’Étude de la Médecine Expérimentale] (1865)
 
Added on 30-Jan-15 | Last updated 30-Jan-15
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Theories are only verified hypotheses, verified by more or less numerous facts. Those verified by the most facts are the best, but even then they are never final, never to be absolutely believed.

Claude Bernard (1813-1878) French physiologist, scientist
An Introduction to the Study of Experimental Medicine [Introduction à l’Étude de la Médecine Expérimentale] (1865)
 
Added on 23-Jan-15 | Last updated 23-Jan-15
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Science, my lad, has been built upon many errors; but they are errors which is was good to fall into, for they led to the truth.

Jules Verne (1828-1905) French novelist, poet, playwright
Journey to the Center of the Earth [Voyage au centre de la Terre], ch. 30 [Liedenbrock] (1864)
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Alt. trans.: "Science, my lad, is made up of mistakes, but they are mistakes which it is useful to make, because they lead little by little to the truth."
 
Added on 30-Dec-14 | Last updated 30-Dec-14
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What do you think science is? There is nothing magical about science. It is simply a systematic way for carefully and thoroughly observing nature and using consistent logic to evaluate results. So which part of that exactly do you disagree with? Do you disagree with being thorough? Using careful observation? Being systematic? Or using consistent logic?

Steven Novella (b. 1964) American clinical neurologist, academic, skeptic
The Skeptics’ Guide to the Universe Podcast, #292 (16 Feb 2011)
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Added on 24-Jun-14 | Last updated 24-Jun-14
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There should be no articles of faith in science, unless it be the faith that no discovery, no law, is so absolute that it cannot be superseded.

Anthony Storr (1920-2001) English psychiatrist and author
Feet of Clay: Saints, Sinners and Madmen, ch. 10 (1996)
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Added on 19-Feb-14 | Last updated 11-Feb-21
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The great and peculiar benefit which a fair course of scientific study confers, even on those who do not follow it as a profession, is that it compels such a firm and entire faith in our mental processes, so far as their range extends, that it teaches us what this range is, and enables us to distinguish between the natural and the artificial limitations of man’s powers. And let me bid you remember that this faith does not rest upon mere testimony, however respectable, however solemnly supported. The works of science are her witness. Her age of inspiration and of miracles is not over, but beginning, and its duration will be coeval with that of the intellect of man. Nor is access to her deepest secrets restricted to a race or to a priesthood. Every man can, if he pleases, apply to the sources of all scientific knowledge directly, and verify for himself the conclusions of others. In science, faith is based solely on the assent of the intellect; and the most complete submission to ascertained truth is wholly voluntary, because it is accompanied by perfect freedom, nay, by every encouragement, to test and try that truth to the uttermost.

T. H. Huxley (1825-1895) English biologist [Thomas Henry Huxley]
“Science and Religion,” lecture (Dec 1858)
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Quoted in The Government School of Mines, The Builder (Jan 1859)
 
Added on 31-Jan-14 | Last updated 31-Jan-14
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If you have a good scientific imagination, you can think of all sorts of things that might be true, and that’s the essence of science. You first think of something that might be true — then you look to see if it is, and generally it isn’t.

Bertrand Russell
Bertrand Russell (1872-1970) English mathematician and philosopher
Interview by Woodrow Wyatt, BBC TV (1959)

Collected in Bertrand Russell's BBC Interviews (1959) [UK] and Bertrand Russell Speaks His Mind (1960) [US].
 
Added on 15-Jan-14 | Last updated 9-Aug-23
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The man of science has learned to believe in justification, not by faith, but by verification.

T. H. Huxley (1825-1895) English biologist [Thomas Henry Huxley]
“On the Advisableness of Improving Natural Knowledge” (1870)
 
Added on 18-Dec-13 | Last updated 18-Dec-13
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That is the essence of science: ask an impertinent question, and you are on the way to a pertinent answer.

Jacob Bronowski (1908-1974) Polish-English humanist and mathematician
The Ascent of Man ch. 4 (1973)
 
Added on 20-Nov-13 | Last updated 1-Dec-15
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Not that indeed I imitated the sceptics, who only doubt for the sake of doubting, and pretend to be always uncertain; for, on the contrary, my design was only to provide myself with good ground for assurance, and to reject the quicksand and mud in order to find the rock or clay.

[Non que j’imitasse pour cela les sceptiques, qui ne doutent que pour douter, et affectent d’être toujours irrésolus; car, au contraire, tout mon dessein ne tendoit qu’à m’assurer, et à rejeter la terre mouvante et le sable pour trouver le roc ou l’argile.]

René Descartes (1596-1650) French philosopher, mathematician
Discourse on Method [Discours de la méthode], Part 3 (1637) [tr. Haldane & Ross (1911)]
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(Source (French)). Alternate translations:

Not that I therein imitated the Scepticks, who doubt onely to the end they may doubt, and affect to be always unresolved: For on the contrary, all my designe tended onely to fix my self, and to avoid quick-mires and sands, that I might finde rock and clay.
[tr. Newcombe ed. (1649)]

Not that in this I imitated the sceptics who doubt only that they may doubt, and seek nothing beyond uncertainty itself; for, on the contrary, my design was singly to find ground of assurance, and cast aside the loose earth and sand, that I might reach the rock or the clay.
[tr. Veitch (1901)]

For all that, I did not imitate the sceptics who doubt only for doubting's sake, and pretend to be always undecided; on the contrary, my whole intention was to arrive at a certainty, and to dig away the drift and the sand until I reached the rock or the clay beneath.
[tr. Huxley (1870)]

In doing this I was not copying the sceptics, who doubt only for the sake of doubting and pretend to be always undecided; on the contrary, my whole aim was to reach certainty -- to cast aside the loose earth and sand so as to come upon rock or clay.
[tr. Cottingham, Stoothoff (1985)]

 
Added on 28-Dec-12 | Last updated 4-Jun-22
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But there is one feature I notice that is generally missing in Cargo Cult Science. That is the idea that we all hope you have learned in studying science in school — we never explicitly say what this is, but just hope that you catch on by all the examples of scientific investigation. It is interesting, therefore, to bring it out now and speak of it explicitly. It’s a kind of scientific integrity, a principle of scientific thought that corresponds to a kind of utter honesty — a kind of leaning over backwards. For example, if you’re doing an experiment, you should report everything that you think might make it invalid — not only what you think is right about it: other causes that could possibly explain your results; and things you thought of that you’ve eliminated by some other experiment, and how they worked — to make sure the other fellow can tell they have been eliminated.

Richard Feynman (1918-1988) American physicist
“Cargo Cult Science,” commencement address, California Institute of Technology (1974)
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Added on 1-Nov-07 | Last updated 10-Jan-20
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The inexperienced, and crackpots, and people like that, make guesses that are simple, but you can immediately see that they are wrong, so that does not count. Others, the inexperienced students, make guesses that are very complicated, and it sort of looks as if it is all right, but I know it is not true because the truth always turns out to be simpler than you thought.

Richard Feynman (1918-1988) American physicist
The Character of Physical Law, ch 7 “Seeking New Laws” (1965)
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Added on 1-Feb-04 | Last updated 10-Jan-20
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History warns us, however, that it is the customary fate of new truths to begin as heresies and to end as superstitions; and, as matters now stand, it is hardly rash to anticipate that, in another twenty years, the new generation, educated under the influences of the present day, will be in danger of accepting the main doctrines of the ‘Origin of Species’ with as little reflection, and it may be with as little justification, as so many of our contemporaries, twenty years ago, rejected them. Against any such a consummation let us all devoutly pray; for the scientific spirit is of more value than its products, and irrationally held truths may be more harmful than reasoned errors.

T. H. Huxley (1825-1895) English biologist [Thomas Henry Huxley]
“The Coming of Age of The Origin of Species,” lecture, Royal Institution (19 Mar 1880)
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First printed in Nature: A Weekly Illustrated Journal of Science (6 May 1880).
 
Added on 1-Feb-04 | Last updated 24-Nov-21
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