… [P]riests of the different religious sects, who dread the advance of science as witches do the approach of day-light; and scowl on the fatal harbinger announcing the subversion of the duperies on which they live.

Thomas Jefferson (1743-1826) American political philosopher, polymath, statesman, US President (1801-09)

Letter to José Corrêa da Serra (11 Apr 1820)
    (Source)

On resistance, particularly from Presbyterians, to the founding of the University of Virginia.