I have a post over on my main blog about problems with the .info top-level domain being associated with spamming and malware — even though there are perfectly legitimate users of it (such as WIST, and New York’s MTA), and the rate of “bad stuff” isn’t all that much higher than from .com domains.
The current problem is that some software vendors and hosts are actually discriminating or blocking things associated with .info, e.g., Microsoft’s Windows Live Messenger, as well as some mail systems that block or downcheck e-mail from a .info domain.
I don’t plan on changing the WIST site any time soon — but I will be monitoring the situation.