The second office of the government is honorable & easy, the first is but a splendid misery.

Thomas Jefferson (1743-1826) American political philosopher, polymath, statesman, US President (1801-09)
Letter (1797-05-13) to Elbridge Gerry
    (Source)

On the vice-presidency and presidency of the United States. Written after he had lost to John Adams, who became President and him Vice-President.