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No desire is more natural than the desire for knowledge. We assay all the means that can lead us to it. When reason fails us we make use of experience. Experience is a weaker and less dignified means: but truth is so great a matter that we must not disdain any method that leads us to it.

[Il n’est desir plus naturel que le desir de cognoissance. Nous essayons tous les moyens qui nous y peuvent mener. Quand la raison nous faut, nous y employons l’experience. Qui est un moyen de beaucoup plus foible et plus vil. Mais la verité est chose si grande, que nous ne devons desdaigner aucune entremise qui nous y conduise.]

Michel de Montaigne (1533-1592) French essayist
Essays, Book 3, ch. 13 “On Experience [De l’Experience]” (1588) (3.13) (1595) [tr. Screech (1987)]
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Aristotle's Metaphysics opens with the phrase "All men by nature desire knowledge."

The 1595 edition included a quotation from Manilius inserted after the word "experience" (omitted here). It also added the second descriptor (after "weaker") of how experience compares to reason.

(Source (French)). Alternate translations:

There is no desire more naturall, then that of knowledge. We attempt all meanes that may bring us unto it. When reason failes us, we employ experience. Which is a meane by much more, weake and vile. But trueth is of so great consequence, that wee ought not disdaine any induction, that may bring us unto it.
[tr. Florio (1603)]

There is no Desire more natural than that of Knowledge: We try all Ways that can lead us to it; where Reason is wanting, we therein employ Experience which is a Means much more weak and cheap. But Truth is so great a thing, that we ought not to disdain any Mediation that will guide us to it.
[tr. Cotton (1686)]

There is no desire more natural than that of knowledge. We try all ways that can lead us to it; where reason is wanting, we therein employ experience which is a means much more weak and cheap; but truth is so great a thing, that we ought not to disdain any mediation that will guide us to it.
[tr. Cotton/Hazlitt (1877)]

There is no desire more natural than the desire for knowledge. We make trial of all means that can lead us to it. When reasoning fails us, we then make use of experience, which is a much feebler and lower means; but truth is so great a thing that we must not disdain any medium that leads us to it.
[tr. Ives (1925)]

There is no desire more natural than the desire for knowledge. We try all the ways that can lead us to it. When reason fails us, we use experience, which is a weaker and less dignified means. But truth is so great a thing that we must not disdain any medium that will lead us to it.
[tr. Frame (1943)]

 
Added on 23-Feb-24 | Last updated 14-Mar-24
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If you do not expect the unexpected, you will not find it; for it is hard to be sought out and difficult.
 
[ἐὰν μὴ ἔλπηται ἀνέλπιστον οὐκ ἐξευρήσει, ἀνεξερεύνητον ἐὸν καὶ ἄπορον]

Heraclitus of Ephesus (c.540-c.480 BC) Greek philosopher [Ἡράκλειτος, Herákleitos, Heracleitus]
Fragment 18 [tr. Burnet (1920), DK B18]
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(Source (Greek)). Alternate translations:

He who does not expect will not find out the unexpected, for it is trackless and unexplored.
[tr. Kahn (1981), VI (D. 18)]

He who does not expect the unexpected will not find it out.
[tr. Kahn (1981), VI (D. 18), variant]

He who does not expect the unexpected will not find it, since it is trackless and unexplored.
[tr. Allan (2008)]

Unless you expect the unexpected, you will not find it, for it is hidden and thickly tangled.
[tr. Jenks (2014)]

 
Added on 14-Dec-23 | Last updated 14-Dec-23
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What had men thought? What had men believed? How did they come by those thoughts and beliefs? How had men learned to govern themselves? Were the processes the same everywhere?

Did man build cities because of an inner drive, like that of a beaver to build dams? How much of what we do is free will, and how much is programmed in our genes? Why is each people so narrow that it believes that it, and it alone, has all the answers? In religion, is there but one road to salvation? Or are there many, all equally good, all going in the same general direction?

I have read my books by many lights, hoarding their beauty, their wit or wisdom against the dark days when I would have no book, nor a place to read.

I have known hunger of the belly kind many times over, but I have known a worse hunger: the need to know and to learn.

Louis L'Amour (1908-1988) American writer
Education of a Wandering Man: A Memoir, ch. 11 (1989)
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Added on 29-Aug-23 | Last updated 29-Aug-23
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Liberal learning is both a safeguard against false ideas of freedom and a source of true ones.

Whitney Griswold
Whitney Griswold (1906–1963) American historian, educator [Alfred Whitney Griswold]
“Freedom, Security, and the University Tradition,” speech, Columbia University Bicentennial (1954-06-02)
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Reprinted in Griswold, In the University Tradition (1957).

Quoted by John F. Kennedy in a speech at Yale University (1962-06-11). Citations of Kennedy for the quote are far more common than for Griswold's original.
 
Added on 16-May-23 | Last updated 16-May-23
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Since the earliest days, philosophers have dreamed of a country where the mind and spirit of man would be free; where there would be no limits to inquiry; where men would be free to explore the unknown and to challenge the most deeply rooted beliefs and principles. Our First Amendment was a bold effort to adopt this principle — to establish a country with no legal restrictions of any kind upon the subjects people could investigate, discuss, and deny.

Hugo Black (1886-1971) American politician and jurist, US Supreme Court Justice (1937-71)
James Madison Lecture, NYU School of Law (1960-02-17)
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The inaugural Madison lecture. Reprinted as "The Bill of Rights," NYU Law Review, Vol. 35 (Apr 1960)
 
Added on 16-Mar-23 | Last updated 4-May-23
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Where shall wisdom be found, and where is the place of understanding? If I knew, I’d walk over and stand there. As it was, I felt as if I stood in the midst of a large map, surrounded by vague areas wherein were penned the visages of particularly nasty-looking random variables. A perfect place for a soliloquy, if one had anything to say.

Roger Zelazny (1937-1995) American writer
The Blood of Amber, ch. 5 (1986)
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Quoting Job 28:12.
 
Added on 6-Apr-22 | Last updated 6-Apr-22
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We cannot have a society half slave and half free; nor can we have thought half slave and half free. If we create an atmosphere in which men fear to think independently, inquire fearlessly, express themselves freely, we will in the end create the kind of society in which men no longer care to think independently or to inquire fearlessly.

Henry Steele Commager (1902-1998) American historian, writer, activist
“What Ideas Are Safe?” Saturday Review (5 Nov 1949)
    (Source)

Reprinted in Freedom and Order (1966).
 
Added on 23-Mar-22 | Last updated 23-Mar-22
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Inquiry into the evidence of a doctrine is not to be made once for all, and then taken as finally settled. It is never lawful to stifle a doubt; for either it can be honestly answered by means of the inquiry already made, or else it proves that the inquiry was not complete.

“But,” says one, “I am a busy man; I have no time for the long course of study which would be necessary to make me in any degree a competent judge of certain questions, or even able to understand the nature of the arguments.” Then he should have no time to believe.

William Kingdon Clifford (1845-1879) English mathematician and philosopher
“The Ethics of Belief,” Part 1 “The Duty of Inquiry,” Lecture, London (11 Apr 1876)
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Added on 6-Dec-21 | Last updated 6-Dec-21
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Above all, the search after truth and its eager pursuit are peculiar to man. And so, when we have leisure from the demands of business cares, we are eager to see, to hear, to learn something new, and we esteem a desire to know the secrets or wonders of creation as indispensable to a happy life. Thus we come to understand that what is true, simple, and genuine appeals most strongly to a man’s nature.

[In primisque hominis est propria veri inquisitio atque investigatio. Itaque cum sumus necessariis negotiis curisque vacui, tum avemus aliquid videre, audire, addiscere cognitionemque rerum aut occultarum aut admirabilium ad beate vivendum necessarian! ducimus. Ex quo intellegitur, quod verum, simplex sincerumque sit, id esse naturae hominis aptissimum.]

Marcus Tullius Cicero (106-43 BC) Roman orator, statesman, philosopher
De Officiis [On Duties; On Moral Duty; The Offices], Book 1, ch. 4 (1.4) / sec. 13 (44 BC) [tr. Miller (1913)]
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Original Latin. Alt. trans.:

But of all the properties and inclinations of men, there is none more natural and peculiar to them than an earnest desire and search after truth. Hence it is that our minds are no sooner free from the thoughts and engagements of necessary business, but we presently long to be either seeing, or hearing, or learning of something; and esteem the knowledge of things secret and wonderful as a necessary ingredient of a happy life. Whence it appears that nothing is more agreeable and suited to the nature and minds of men than undisguised openness, truth, and sincerity.
[tr. Cockman (1699)]

The desire and investigation of truth is proper to man. When disengaged from necessary business and cares, we are eager to add to our knowledge by examining for ourselves or listening to others. The discovery of what is secret or wonderful, we are disposed to conceive essential to happiness. Hence, what is true, simple, and undisguised, is best adapted to human nature.
[tr. McCartney (1798)]

Before all other things, man is distinguished by his pursuit and investigation of TRUTH. And hence, when free from needful business and cares, we delight to see, to hear, and to communicate, and consider a knowledge of many admirable and abstruse things necessary to the good conduct and happiness of our lives: whence it is clear that whatsoever is TRUE, simple, and direct, the same is most congenial to our nature as men.
[In John Frederick William Herschel, A Preliminary Discourse on the Study of Natural Philosophy, Epigraph (1830)]

The distinguishing property of man is to search for and to follow after truth. Therefore, when relaxed from our necessary cares and concerns, we then covet to see, to hear, and to learn somewhat; and we esteem knowledge of things either obscure or wonderful to be the indispensable means of living happily. From this we understand that truth, simplicity, and candour, are most agreeable to the nature of mankind.
[tr. Edmonds (1865)]

The research and investigation of truth, also, are a special property of man. Thus, when we are free from necessary occupations, we want to see, or hear, or learn something, and regard the knowledge of things either secret or wonderful as essential to our living happily and well.
[tr. Peabody (1883)]

The distinctive faculty of man is his eager desire to investigate the truth. Thus, when free from pressing duties and cares, we are eager to see or hear, or learn something new, and we think our happiness is incomplete unless we study the mysteries and the marvels of the universe.
[tr. Gardiner (1899)]

The first duty of man is the seeking after and the investigation of truth.
[ed. Harbottle (1906)

Inquiry into and searching for truth are primary characteristics of mankind. So when we are free from business obligations and other preoccupations, we become eager to see something new, to hear and learn something; we begin to think that knowledge about the mysteries and wonders of the world is necessary to a happy life.
[tr. Edinger (1974)]

 
Added on 4-Jan-21 | Last updated 8-Sep-22
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There is nobody, in the commonwealth of learning, who does not profess himself a lover of truth, — and there is not a rational creature, that would not take it amiss, to be thought otherwise of. And yet, for all this, one may truly say, there are very few lovers of truth, for truth-sake, even amongst those who persuade themselves that they are so. How a man may know, whether he be so, in earnest, is worth inquiry; and I think, there is this one unerring mark of it, viz. the not entertaining any proposition with greater assurance than the proofs it is built on will warrant. Whoever goes beyond this measure of assent, it is plain, receives not truth in the love of it, loves not truth for truth-sake, but for some other by-end.

John Locke (1632-1704) English philosopher
An Essay Concerning Human Understanding, Book 4 “Of Knowledge and Opinion,” ch. 19 “Of Enthusiasm,” sec. 1 “Love of truth necessary” (1689)
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Added on 1-Jun-20 | Last updated 1-Jun-20
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No man holding a strong belief on one side of a question, or even wishing to hold a belief on one side, can investigate it with such fairness and completeness as if he were really in doubt and unbiased; so that the existence of a belief not founded on fair inquiry unfits a man for the performance of this necessary duty.

William Kingdon Clifford (1845-1879) English mathematician and philosopher
“The Ethics of Belief,” Part 1 “The Duty of Inquiry,” Contemporary Review (Jan 1877)
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Added on 13-Mar-20 | Last updated 13-Mar-20
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Science is the belief in the ignorance of the experts.

Richard Feynman (1918-1988) American physicist
“What Is Science?” address, National Science Teachers Association, New York (1966)
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Added on 4-Mar-20 | Last updated 4-Mar-20
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Better ask twice than lose your way once.

(Other Authors and Sources)
Danish Proverb
 
Added on 5-Feb-20 | Last updated 5-Feb-20
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One of the greatest of joys known to man is to take such a flight into ignorance in search of knowledge. The great pleasure of ignorance is, after all, the pleasure of asking questions. The man who has lost this pleasure or exchanged it for the pleasure of dogma, which is the pleasure of answering, is already beginning to stiffen.

Robert Lynd (1892-1970) American sociologist [Robert Slaughton Lynd]
The Pleasure of Ignorance, ch. 1 (1921)
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Added on 29-Jan-20 | Last updated 29-Jan-20
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But your spiritual teachers caution you against enquiry — tell you not to read certain books; not to listen to certain people; to beware of profane learning; to submit your reason, and to receive their doctrines for truths. Such advice renders them suspicious counsellors. By their own creed, you hold your reason from their God. Go! ask them why he gave it.

Frances "Fanny" Wright (1795-1852) Scottish-American writer, lecturer, social reformer
A Course of Popular Lectures, Lecture 3 “Of the more Important Divisions and Essential Parts of Knowledge” (1829)
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Added on 4-Sep-19 | Last updated 4-Sep-19
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The desire of knowledge, like the thirst of riches, increases ever with the acquisition of it.

Sterne - desire of knowledge - wist_info quote

Laurence Sterne (1713-1786) Anglo-Irish novelist, Anglican clergyman
Tristam Shandy, Book 1, ch. 3 (1760-1767)
 
Added on 3-Mar-16 | Last updated 3-Mar-16
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Albert grunted. “Do you know what happens to lads who ask too many questions?”

Mort thought for a moment. “No,” he said eventually, “what?”

There was silence.

Then Albert straightened up and said, “Damned if I know. Probably they get answers, and serve ’em right.”

Terry Pratchett (1948-2015) English author
Mort (1987)
 
Added on 22-Jul-15 | Last updated 22-Jul-15
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To ask the right question is already half the solution of a problem.

Carl Jung (1875-1961) Swiss psychologist
Archetypes of the Collective Unconscious (1934) [tr. Hull (1959)]
 
Added on 23-Mar-15 | Last updated 23-Mar-15
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Do not be frightened from this inquiry by any fear of its consequences. If it ends in a belief that there is no god, you will find incitements to virtue in the comfort and pleasantness you feel in its exercise, and the love of others which it will procure you. If you find reason to believe there is a God, a consciousness that you are acting under his eye, and that he approves you, will be a vast additional incitement; if that there be a future state, the hope of a happy existence in that increases the appetite to deserve it; if that Jesus was also a god, you will be comforted by a belief of his aid and love.

Thomas Jefferson (1743-1826) American political philosopher, polymath, statesman, US President (1801-09)
Letter to Peter Carr (10 Aug 1787)
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Added on 27-Jun-13 | Last updated 2-Aug-22
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Read the bible then, as you would read Livy or Tacitus. The facts which are within the ordinary course of nature you will believe on the authority of the writer, as you do those of the same kind in Livy and Tacitus. The testimony of the writer weighs in their favor in one scale, and their not being against the laws of nature does not weigh against them. But those facts in the bible which contradict the laws of nature, must be examined with more care, and under a variety of faces. Here you must recur to the pretensions of the writer to inspiration from god. Examine upon what evidence his pretensions are founded, and whether that evidence is so strong as that it’s falshood would be more improbable than a change of the laws of nature in the case he relates For example in the book of Joshua we are told the sun stood still several hours. Were we to read that fact in Livy or Tacitus we should class it with their showers of blood, speaking of statues, beasts &c., but it is said that the writer of that book was inspired. Examine therefore candidly what evidence there is of his having been inspired. The pretension is entitled to your enquiry, because millions believe it. On the other hand you are Astronomer enough to know how contrary it is to the law of nature that a body revolving on it’s axis, as the earth does, should have stopped, should not by that sudden stoppage have prostrated animals, trees, buildings, and should after a certain time have resumed it’s revolution, and that without a second general prostration. Is this arrest of the earth’s motion, or the evidence which affirms it, most within the law of probabilities?

Thomas Jefferson (1743-1826) American political philosopher, polymath, statesman, US President (1801-09)
Letter to Peter Carr (10 Aug 1787)
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Added on 13-Jun-13 | Last updated 2-Aug-22
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Questions show the mind’s range, and answers, its subtlety.
 
[Les questions montrent l’étendue de l’esprit, et les réponses sa finesse.]

Joseph Joubert (1754-1824) French moralist, philosopher, essayist, poet
Pensées [Thoughts], ch. 4 “De la Nature des Esprits [On the Nature of Minds],” ¶ 62 (1850 ed.) [tr. Lyttelton (1899), ch. 3, ¶ 21]
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(Source (French))

While confirmed as an entry in the French, I was unable to find translations other than Lyttelton's in my various sources.
 
Added on 13-May-13 | Last updated 30-Jan-24
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I have seen several entirely sincere people who thought they were (permanent) Seekers after Truth. They sought diligently, persistently, carefully, cautiously, profoundly, with perfect honesty and nicely adjusted judgment — until they believed that without doubt or question they had found the Truth.

That was the end of the search. The man spent the rest of his life hunting up shingles wherewith to protect his Truth from the weather. If he was seeking after political Truth he found it in one or another of the hundred political gospels which govern men in the earth; if he was seeking after the Only True Religion he found it in one or another of the three thousand that are on the market. In any case, when he found the Truth he sought no further; but from that day forth, with his soldering-iron in one hand and his bludgeon in the other he tinkered its leaks and reasoned with objectors.

Mark Twain (1835-1910) American writer [pseud. of Samuel Clemens]
“What is Man?” (1906)
 
Added on 28-May-08 | Last updated 26-Jan-19
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Risk for risk, for myself I had rather take my chance that some traitors will escape detection than spread abroad a spirit of general suspicion and distrust, which accepts rumor and gossip in place of undismayed and unintimidated inquiry.

Learned Hand (1872-1961) American jurist
“A Plea for the Open Mind and Free Discussion,” speech, University of the State of New York, Albany (1952-10-24)
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Added on 20-Feb-08 | Last updated 27-Mar-23
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In fine, I repeat that you must lay aside all prejudice on both sides, and neither believe nor reject any thing because any other person, or description of persons have rejected or believed it. Your own reason is the only oracle given you by heaven, and you are answerable not for the rightness but uprightness of the decision.

Thomas Jefferson (1743-1826) American political philosopher, polymath, statesman, US President (1801-09)
Letter to Peter Carr (10 Aug 1787)
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On urging him to read and determine for himself the divinity or non-divinity of Christ.
 
Added on 1-Feb-04 | Last updated 24-Jul-22
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If a man, holding a belief which he was taught in childhood or persuaded of afterwards, keeps down and pushes away any doubts which arise about it in his mind, purposely avoids the reading of books and the company of men that call in question and discuss it, and regards as impious those questions which cannot easily be asked without disturbing it — the life of that man is one long sin against mankind.

William Kingdon Clifford (1845-1879) English mathematician and philosopher
“The Ethics of Belief,” Part 1 “The Duty of Inquiry,” Contemporary Review (Jan 1877)
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Added on 1-Feb-04 | Last updated 10-Jan-20
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The Framers knew, better perhaps than we do today, the risks they were taking. They knew that free speech might be the friend of change and revolution. But they also knew that it is always the deadliest enemy of tyranny. With this knowledge they still believed that the ultimate happiness and security of a nation lies in its ability to explore, to change, to grow and ceaselessly to adapt itself to new knowledge born of inquiry free from any kind of governmental control over the mind and spirit of man. Loyalty comes from love of good government, not fear of a bad one.

Hugo Black (1886-1971) American politician and jurist, US Supreme Court Justice (1937-71)
James Madison Lecture, NYU School of Law (1960-02-17)
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The inaugural Madison lecture. Reprinted as "The Bill of Rights," NYU Law Review, Vol. 35 (Apr 1960).
 
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Inquiry is fatal to certainty.

William James (Will) Durant (1885-1981) American historian, teacher, philosopher
The Age of Faith, ch. 38 “The Age of Romance” (1950)
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Added on 1-Feb-04 | Last updated 13-Jul-23
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Ask a question and you’re a fool for three minutes; do not ask a question and you’re a fool for the rest of your life.

(Other Authors and Sources)
Chinese proverb
 
Added on 1-Feb-04 | Last updated 11-Feb-20
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